During sexual arousal, nitric oxide is released in the erectile tissue of the penis, which stimulates the production of cGMP. This leads to relaxation of the smooth muscles in the penile arteries, allowing for increased blood flow into the penis and the subsequent erection. However, in men with ED, the activity of PDE5 can prematurely degrade cGMP, leading to difficulty in achieving and maintaining an erection.
Fildena contains sildenafil citrate, which is a PDE5 inhibitor. By blocking the action of PDE5, Fildena helps to preserve the levels of cGMP in the penis, allowing for sustained relaxation of the penile arteries and increased blood flow during sexual stimulation. This facilitates the ability to achieve and maintain an erection sufficient for satisfactory sexual activity.
